2023
- Maniv I, Sarji M, Bdarneh A, Feldman A, Ankawa R, Koren E, Magid-Gold I, Reis N, Soteriou D, Salomon-Zimri S, Lavy T, Kesselman E, Koifman N, Kurz T, Kleifeld O, Michaelson D, van Leeuwen FW, Verheijen BM, Fuchs Y, Glickman MH. Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model. Nat Commun. 2023 Sep 22;14(1):5922. doi: 10.1038/s41467-023-41545-7. PMID: 37739965.
- Choi WH, Yun Y, Byun I, Kim S, Lee S, Sim J, Levi S, Park SH, Jun J, Kleifeld O, Kim KP, Han D, Chiba T, Seok C, Kwon YT, Glickman MH, Lee MJ. ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation. Cell Rep. 2023 Jun 27;42(7):112701. doi: 10.1016/j.celrep.2023.112701.
- Makaros Y, Raiff A, Timms RT, Wagh AR, Gueta MI, Bekturova A, Guez-Haddad J, Brodsky S, Opatowsky Y, Glickman MH, Elledge SJ, Koren I. Ubiquitin-independent proteasomal degradation driven by C-degron pathways. Mol Cell. 2023 May 9:S1097-2765(23)00317-9. doi: 10.1016/j.molcel.2023.04.023.
- Wagh AR, Sulakshane P, Glickman MH. Alzheimer’s disease-associated mutant ubiquitin (UBB+1) is secreted through an autophagosome-like vesicle-mediated unconventional pathway, Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms. 2023; 194936. https://doi.org/10.1016/j.bbagrm.2023.194936.
- Sahu I, Sahoo MP, Kleifeld O, Glickman MH. Isolation of Proteasome-Trapped Peptides (PTPs) for Degradome Analysis. Methods Mol Biol. 2023;2602:229-241. doi: 10.1007/978-1-0716-2859-1_17.
2022
- Mann G, Sulkshane P, Sadhu P, Ziv T, Glickman MH, Brik A. Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1. Molecules. 2022 Jul 29;27(15):4867. doi: 10.3390/molecules27154867.
- Gold IM, Reis N, Glaser F, Glickman MH. Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15). Semin Cell Dev Biol. 2022 Jun 25:S1084-9521(22)00215-4. doi: 10.1016/j.semcdb.2022.06.005
2021
- Sahu I, Mali SM, Sulkshane P, Xu C, Rozenberg A, Morag R, Sahoo MP, Singh SK, Ding Z, Wang Y, Day S, Cong Y, Kleifeld O, Brik A, Glickman MH. The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag. Nat Commun. 2021 Oct 26;12(1):6173. doi: 10.1038/s41467-021-26427-0.
- Mann G, Satish G, Sulkshane P, Mandal S, Glickman MH, Brik A.
Synthesis and delivery of a stable phosphorylated ubiquitin probe to study ubiquitin conjugation in mitophagy. Chem Commun (Camb). 2021 Sep 16;57(74):9438-9441. doi: 10.1039/d1cc04045f.
- Sulkshane P, Ram J,Thakur A,Reis N, Kleifeld O, Glickman MH. Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia. Redox Biology. 2021 June 17: https://doi.org/10.1016/j.redox.2021.102047
- Sahu I and Glickman MH. Proteasome in action: substrate degradation by the 26S proteasome. Biochem Soc Trans. 2021 Mar 17:BST20200382. doi: 10.1042/BST20200382.
- Structural Insights into Substrate Recognition and Processing by the 20S Proteasome. Biomolecules. 2021 Jan 24;11(2):148. doi: 10.3390/biom11020148 [Review]
2020
- Sulkshane P, Ram J, Glickman MH. Ubiquitination of Intramitochondrial Proteins: Implications for Metabolic Adaptability. Biomolecules. 2020 Nov 16;10(11):1559. doi: 10.3390/biom10111559 [Review]
- Vamisetti GB, Satish G, Sulkshane P, Mann G, Glickman MH, Brik A. On-Demand Detachment of Succinimides on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins. J Am Chem Soc. 2020 Nov 18;142(46):19558-19569. doi: 10.1021/jacs.0c07663. Epub 2020 Nov 2.
- Sulkshane P, Duek I, Ram J, Thakur A, Reis N, Ziv T, Glickman MH. Inhibition of proteasome reveals basal mitochondrial ubiquitination. J Proteomics. 2020 Oct 30;229:103949. doi: 10.1016/j.jprot.2020.103949. Epub 2020 Aug 31.