2011-2015

  • Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E et al: Base-CP proteasome can serve as a platform for stepwise lid formation. Biosci Rep 2015, 35(3).
  • Peters LZ, Karmon O, David-Kadoch G, Hazan R, Yu T, Glickman MH, Ben-Aroya S: The protein quality control machinery regulates its misassembled proteasome subunits. PLoS Genet 2015, 11(4):e1005178.
  • Bondalapati S, Mansour W, Nakasone MA, Maity SK, Glickman MH, Brik A: Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases. Chemistry 2015, 21(20):7360-7364.
  • Nowicka U, Zhang D, Walker O, Krutauz D, Castaneda CA, Chaturvedi A, Chen TY, Reis N, Glickman MH, Fushman D: DNA-damage-inducible 1 protein (Ddi1) contains an uncharacteristic ubiquitin-like domain that binds ubiquitin. Structure 2015, 23(3):542-557.
  • Mansour W, Nakasone MA, von Delbruck M, Yu Z, Krutauz D, Reis N, Kleifeld O, Sommer T, Fushman D, Glickman MH: Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6. J Biol Chem 2015, 290(8):4688-4704.
  • Krutauz D, Reis N, Nakasone MA, Siman P, Zhang D, Kirkpatrick DS, Gygi SP, Brik A, Fushman D, Glickman MH: Extended ubiquitin species are protein-based DUB inhibitors. Nat Chem Biol 2014, 10(8):664-670.
  • Livnat-Levanon N, Kevei E, Kleifeld O, Krutauz D, Segref A, Rinaldi T, Erpapazoglou Z, Cohen M, Reis N, Hoppe T et al: Reversible 26S proteasome disassembly upon mitochondrial stress. Cell Rep 2014, 7(5):1371-1380.
  • Segref A, Kevei E, Pokrzywa W, Schmeisser K, Mansfeld J, Livnat-Levanon N, Ensenauer R, Glickman MH, Ristow M, Hoppe T: Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system. Cell Metab 2014, 19(4):642-652.
  • Weberruss MH, Savulescu AF, Jando J, Bissinger T, Harel A, Glickman MH, Enenkel C: Blm10 facilitates nuclear import of proteasome core particles. EMBO J 2013, 32(20):2697-2707.
  • Bagola K, von Delbruck M, Dittmar G, Scheffner M, Ziv I, Glickman MH, Ciechanover A, Sommer T: Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases. Mol Cell 2013, 50(4):528-539.
  • Nakasone MA, Livnat-Levanon N, Glickman MH, Cohen RE, Fushman D: Mixed-linkage ubiquitin chains send mixed messages. Structure 2013, 21(5):727-740.
  • Karpov D, Glickman MH, Bar-Nun S, Coffino P: Ubiquitin proteasome system in stress and disease. Biochem Res Int 2012, 2012:454796.
  • Singh RK, Zerath S, Kleifeld O, Scheffner M, Glickman MH, Fushman D: Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system. Mol Cell Proteomics 2012, 11(12):1595-1611.
  • Leboucher GP, Tsai YC, Yang M, Shaw KC, Zhou M, Veenstra TD, Glickman MH, Weissman AM: Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis. Mol Cell 2012, 47(4):547-557.
  • He J, Kulkarni K, da Fonseca PC, Krutauz D, Glickman MH, Barford D, Morris EP: The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain as a closed toroid of two concentric alpha-helical rings. Structure 2012, 20(3):513-521.
  • Rosenzweig R, Bronner V, Zhang D, Fushman D, Glickman MH: Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome. J Biol Chem 2012, 287(18):14659-14671.
  • Bar-Nun S, Glickman MH: Proteasomal AAA-ATPases: structure and function. Biochim Biophys Acta 2012, 1823(1):67-82.
  • Keren-Kaplan T, Attali I, Motamedchaboki K, Davis BA, Tanner N, Reshef Y, Laudon E, Kolot M, Levin-Kravets O, Kleifeld O, Glickman M, Horazdovsky BF, Wolf DA, Prag G:¬†Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria, EMBO J¬†2011 Nov 11. doi: 10.1038
  • Deriziotis P, Andre R, Smith DM, Goold R, Kinghorn KJ, Kristiansen M, Nathan JA, Rosenzweig R, Krutauz D, Glickman MH et al: Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry. EMBO J 2011, 30(15):3065-3077.
  • Cohen MM, Amiott EA, Day AR, Leboucher GP, Pryce EN, Glickman MH, McCaffery JM, Shaw JM, Weissman AM: Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion. J Cell Sci 2011, 124(Pt 9):1403-1410.
  • Ziv I, Matiuhin Y, Kirkpatrick DS, Erpapazoglou Z, Leon S, Pantazopoulou M, Kim W, Gygi SP, Haguenauer-Tsapis R, Reis N et al: A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Mol Cell Proteomics 2011, 10(5):M111 009753.
  • Savulescu AF, Glickman MH: Proteasome activator 200: the heat is on. Mol Cell Proteomics 2011, 10(5):R110 006890.
  • Savulescu AF, Shorer H, Kleifeld O, Cohen I, Gruber R, Glickman MH, Harel A: Nuclear import of an intact preassembled proteasome particle. Mol Biol Cell 2011, 22(6):880-891.
  • Yu Z, Kleifeld O, Lande-Atir A, Bsoul M, Kleiman M, Krutauz D, Book A, Vierstra RD, Hofmann K, Reis N et al: Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome. Mol Biol Cell 2011, 22(7):911-920.